by Jason Wasserman MD PhD FRCPC
April 21, 2022
Cylindroma is a non-cancerous type of skin tumour. The tumour develops from sweat glands normally found in the skin. People with Brooke–Spiegler syndrome commonly develop multiple cylindromas. This syndrome is associated with an alteration in the gene CLYD.
Cylindromas are typically found on the head and neck but the upper chest and back can also be involved.
The diagnosis is usually made after the entire tumour has been removed in a procedure called an excision. The diagnosis can also be made after only a small part of the tumour is removed in a procedure called a biopsy.
The microscopic appearance of a cylindroma.
A margin is any tissue that was cut by the surgeon in order to remove the tumour from your body. A negative margin means there were no tumour cells at the edge of the tissue. A margin is considered positive when there are tumour cells at the edge of the tissue. A positive margin is associated with a higher risk that the tumour will grow back (recur) in the same site after treatment.