by Osama Khan MD and Bibianna Purgina MD FRCPC
June 2, 2023
Giant cell tumour of tendon sheath is a non-cancerous tumour that commonly occurs in the fingers of the hand. It can also involve the large joints of the body such as the knee and elbow. Joints connect two bones together and are important for movement. Although a giant cell tumour of tendon sheath is non-cancerous, a small number of them can grow back at the same location over time. This tumour most commonly affects people in their 30s and 40s and occurs more commonly in females.
Giant cell tumour of tendon sheath is typically diagnosed after a small sample of tissue is removed in a procedure called a biopsy or they are completely removed in a procedure called an excision or resection. They are then examined by a pathologist under the microscope.
Giant cell tumour of tendon sheath is made up of two kinds of cells:
Your pathologist will look for both of these types of cells when examining your tissue sample under the microscope.