by Jason Wasserman MD PhD FRCPC
August 25, 2022
Palmar fibromatosis is a non-cancerous growth found on the flexor (palm) side of the hand. Other names for this condition are Dupuytren’s disease or Dupuytren’s contracture.
No. Palmar fibromatosis is a non-cancerous growth.
These two conditions are very similar. However, palmar fibromatosis involves the hand while plantar fibromatosis involves the foot.
Palmar fibromatosis may be associated with diabetes, cigarette smoking, alcoholism, and repetitive trauma to the hand. However, at present, the cause of palmar fibromatosis remains unknown.
For most people, palmar fibromatosis develops slowly over time with very few symptoms. Later, small painless bumps may be seen on the flexor side (palm) of the hand. If left untreated contractures may develop. These are abnormally firm areas of tissue that often prevent the fingers from moving normally.
Your doctor may suspect that you have palmar fibromatosis after talking to you and examining your hands. The diagnosis can also be made after the abnormal tissue is surgically removed and sent to a pathologist for examination under the microscope.
When examined under the microscope, palmar fibromatosis is made up of specialized cells called fibroblasts or myofibroblasts surrounded by a type of connective tissue called collagen. Most pathology reports use the term spindle cells to describe these cells because they are long and thin. The number of both fibroblasts and myofibroblasts is greater early on and decreases over time.