by Adnan Karavelic MD FRCPC
November 28, 2022
Secretory endometrium is a term pathologists use to describe the changes seen in the endometrium during the second half of the menstrual cycle. It is a normal finding in women of reproductive age.
Yes. Secretory endometrium is a normal finding in women of reproductive age.
The function of the secretory endometrium is to produce substances necessary to support the implantation of an egg should conception occur.
After ovulation, the endometrium grows under the influence of progesterone. During this phase, the endometrial glands become long and twisted, and the secretion starts. Pathologists call this phase the secretory endometrium.
The diagnosis of secretory endometrium is usually made after a small sample of tissue is removed from the endometrium during a procedure called an endometrial biopsy or uterine curetting.
Common reasons for these procedures include:
The microscopic changes in the endometrium allow your pathologist to determine how many days it has been since ovulation occurred. This information is called the post-ovulation day and it is especially important for women trying to become pregnant. You may see the post-ovulation date described in your report.