Pathology dictionary

What does LVI mean?

LVI stands for lymphovascular invasion. Lymphovascular invasion is the spread of cancer cells into either a blood or lymphatic vessel.

Normal blood and lymphatic vessels

Blood vessels carry blood to and from organs. Lymphatic vessels bring excess fluid, waste, and other substances away from organs so they can be examined by the immune system before being removed from the body. Lymphatic vessels connect with small immune organs called lymph nodes.

Why is this important? Lymphovascular invasion is important because cancer cells inside of a blood vessel or lymphatic are able to travel to lymph nodes and other parts of the body. Lymphovascular invasion may be associated with worse prognosis.

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