What does hyperchromatic mean?
Most of the genetic material inside a cell is found in a small structure called the nucleus. Pathologists can see the nucleus by adding a stain called H&E to the tissue. Hyperchromatic is a word pathologists use to describe a nucleus that looks darker than normal when examined under the microscope. Another word for hyperchromatic is hyperchromasia.
What causes the nucleus of a cell to become hyperchromatic?
A nucleus can become hyperchromatic for different reasons. Non-cancerous cells often become hyperchromatic when they are injured. Pathologists sometimes describe these cells as reactive. Hyperchromatic cells can also be seen in pre-cancerous conditions such as dysplasia and in many different types of cancers. In these situations, the hyperchromatic cells are used to support the diagnosis.
Related articles
Our work is generously supported by:
