Pathology dictionary -

Signet cell

A signet cell is a special type of cell that is round and filled with a light blue coloured material called mucin. Pathologists can recognize signet cells under the microscope because the mucin pushes the nucleus of the cell to the side which makes the cell look like a 'signet ring'.

 

Signet cells are often found in groups, however, unlike other types of cells they do not stick together. Pathologists call cells that do not stick together discohesive.

Signet cells and cancer

Signet cells are important because some cancers are made up mostly or entirely out of signet cells. For example, signet cells are commonly seen in cancers of the stomach, ovary, and breast.

 

Some other types of cells may look very similar to signet cells and special tests, such as special stains or immunohistochemistry may be required to confirm the presence of true signet cells. A common special stain to look for signet cells is called mucicarmine and it makes the mucin inside the cell easier to see.

Learn more about cancers with signet cells

Other names used for signet cells

Signet cells are also called signet ring cells.

  • Facebook
  • Twitter

Copyright 2017 MyPathologyReport.ca

For more information about this site, contact us at info@mypathologyreport.ca.

Disclaimer: The articles on MyPathologyReport are intended for general informational purposes only and they do not address individual circumstances. The articles on this site are not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the MyPathologyReport site. The articles on MyPathologyReport.ca are intended for use within Canada by residents of Canada only.

Droits d'auteur 2017 MyPathologyReport.ca
Pour plus d'informations sur ce site, contactez-nous à info@mypathologyreport.ca.
Clause de non-responsabilité: Les articles sur MyPathologyReport ne sont destinés qu’à des fins d'information et ne tiennent pas compte des circonstances individuelles. Les articles sur ce site ne remplacent pas les avis médicaux professionnels, diagnostics ou traitements et ne doivent pas être pris en compte pour la prise de décisions concernant votre santé. Ne négligez jamais les conseils d'un professionnel de la santé à cause de quelque chose que vous avez lu sur le site de MyPathologyReport. Les articles sur MyPathologyReport.ca sont destinés à être utilisés au Canada, par les résidents du Canada uniquement.