AE1/AE3 are a pair of antibodies that recognize multiple cytokeratins, intermediate filament proteins found in epithelial cells. Cytokeratins are normally located in the cytoplasm (body) of the epithelial cell. Pathologists perform a test called immunohistochemistry to stain tissues for AE1/AE3 and the pattern and intensity of staining can help identify the presence of epithelial cells …
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Cytokeratins are a group of proteins called intermediate filaments that are normally found inside specialized epithelial cells¬†that make up the lining of many internal and external surfaces of the body, such as the skin, organs, and glands. These proteins provide structural support and protect against mechanical stress, as well as help maintain their shape and …
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