discohesive

Signet ring cells

Signet ring cells are round, discohesive (they don’t stick together) cancerous cells filled with a light blue coloured substance called mucin. The mucin tends to push the nucleus (the part of the cell that holds the genetic material) to the side (pathologists describe these nuclei as ‘eccentric’ or ‘peripheral’). Signet ring cells are epithelial cells; however, …
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