immune cells

White blood cells (WBCs)

White blood cells (WBCs), also known as leukocytes, are a part of the body’s immune system. They help protect the body against infections, fight off pathogens like bacteria and viruses, and play a role in inflammation and allergic reactions. Unlike red blood cells (RBCs), which carry oxygen, white blood cells primarily defend the body against …
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Germinal centers

Germinal centers are specialized structures within lymphoid tissues where B cells (a type of white blood cell) mature and differentiate. These centers play an important role in the body’s immune response by helping train B cells to produce antibodies that target specific pathogens. Where are germinal centers normally found? Germinal centers are typically found within …
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Lymphoblasts

Lymphoblasts are immature cells that develop into lymphocytes, a type of white blood cell that is integral to the immune system. They are part of the body’s adaptive immune response, responsible for fighting infections and providing long-term immunity. Where are lymphoblasts normally found? Lymphoblasts are primarily found in the bone marrow, the soft, spongy center …
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Blasts

In pathology, the term “blasts” refers to immature cells in the early stages of development into mature cells. These cells are typically found in the bone marrow, which is part of the normal process of blood cell formation known as hematopoiesis. Blasts can develop into various types of blood cells, such as red blood cells, white …
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CD45

CD45 is a protein found on the surface of most cells in the immune system, including white blood cells (also called leukocytes). CD45 helps these immune cells communicate and respond appropriately to infections and inflammation. Why do pathologists test for CD45? Pathologists test for CD45 to help determine if cells seen in a tissue sample …
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B cells

B cells are a type of white blood cell and an important part of the body’s immune system. They help protect the body from infections by identifying and responding to harmful substances, such as bacteria and viruses. What do B cells do? B cells play a key role in the immune response. When B cells …
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Inflammation

Inflammation is your body’s natural defense mechanism against injury, irritation, or infection. It is a process in which your immune system sends specialized cells, proteins, and chemical signals to an affected area to protect your body and aid in its healing. Although inflammation is usually beneficial and necessary, it can sometimes cause discomfort or harm …
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