immune cells

White blood cells (WBCs)

White blood cells (WBCs), also known as leukocytes, are a part of the body’s immune system. They help protect the body against infections, fight off pathogens like bacteria and viruses, and play a role in inflammation and allergic reactions. Unlike red blood cells (RBCs), which carry oxygen, white blood cells primarily defend the body against …
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Germinal centers

Germinal centers are specialized structures within lymphoid tissues where B cells (a type of white blood cell) mature and differentiate. These centers play an important role in the body’s immune response by helping train B cells to produce antibodies that target specific pathogens. Where are germinal centers normally found? Germinal centers are typically found within …
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Lymphoblasts

Lymphoblasts are immature cells that develop into lymphocytes, a type of white blood cell that is integral to the immune system. They are part of the body’s adaptive immune response, responsible for fighting infections and providing long-term immunity. Where are lymphoblasts normally found? Lymphoblasts are primarily found in the bone marrow, the soft, spongy center …
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Blasts

In pathology, the term “blasts” refers to immature cells that are in the early stages of development into mature cells. These cells are typically found in the bone marrow, where they are part of the normal process of blood cell formation, known as hematopoiesis. Blasts can develop into various types of blood cells, such as …
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CD45

CD45, also known as leukocyte common antigen (LCA), is a protein that is expressed on the surface of all hematopoietic cells and their progenitors, except erythrocytes (red blood cells) and platelets. Hematopoietic cells include cells of the immune system, such as B cells, T cells, natural killer (NK) cells, monocytes, and granulocytes. CD45 is a …
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B cells

B cells (also called B lymphocytes) are a type of white blood cell and a part of the immune system. These cells contribute to a process called the adaptive immune response that is important for protecting the body against infections. Specifically, these cells contribute to humoral immunity by producing immunoglobulin (antibodies) that recognize and stick to …
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Inflammation

What is inflammation? Inflammation is the natural response of the body’s immune system to injury, infection, or stress. It is a complex process that involves the release of chemicals from immune cells, blood vessels, and other tissues that help to fight off harmful substances and repair damaged tissues. What causes inflammation? Inflammation is caused by …
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