inflammation

What is necrotizing granulomatous inflammation?

Necrotizing granulomatous inflammation is a specific pattern of long-standing or chronic inflammation seen under the microscope. It occurs when the immune system attempts to isolate and eliminate a harmful substance, such as an infection, foreign material, or a component of an autoimmune response. The word “necrotizing” refers to the presence of dead tissue in the …
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Crypt Abscess: Definition

A crypt abscess is a collection of specialized immune cells called neutrophils found inside the crypts of the colon. Crypts are small, tube-shaped glands that line the inside of the colon and help it function properly. When neutrophils accumulate within these crypts, it indicates acute (recent onset or active) inflammation. This condition is commonly observed …
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Inflammatory Cells: Definition

Inflammatory cells are specialized types of white blood cells that migrate into tissues in response to changes, such as an injury, infection, or cancer. Their job is to protect you by fighting germs, removing damaged tissue, and aiding in the healing process. When a pathologist examines a tissue sample under the microscope, they may describe …
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Inflammation: Definition

Inflammation is your body’s natural defense mechanism against injury, irritation, or infection. It is a process in which your immune system sends specialized cells, proteins, and chemical signals to an affected area to protect your body and aid in its healing. Although inflammation is usually beneficial and necessary, it can sometimes cause discomfort or harm …
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Granulation Tissue: Definition

Granulation describes the look of tissue that is healing after an injury. Without a microscope, the tissue usually looks red or pink and it often feels soft to the touch. When examined under a microscope, the tissue is made up of many small blood vessels surrounded by a combination of cells from the immune system. …
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What is acute inflammation?

Acute inflammation is the body’s immediate and natural response to injury, irritation, or infection. It begins within minutes or hours and is the body’s way of protecting itself, sending immune cells and other substances to the area to fight infection and start the healing process. Unlike chronic inflammation, which lasts for months or years, acute …
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