IgA nephropathy, also known as Berger’s disease, is a kidney condition characterized by the accumulation of immunoglobulin A (IgA) in the kidneys. Antibodies are proteins that normally help fight infections. However, in IgA nephropathy, abnormal forms of IgA accumulate in the kidneys, causing inflammation and damage. This inflammation can eventually lead to kidney problems, including …
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Acute T cell-mediated rejection, also known as acute cellular rejection, is a condition in which the body’s immune system attacks the transplanted kidney. This occurs because special immune cells, called T cells, mistakenly identify the transplanted organ as harmful or foreign. When this happens, the T cells enter the kidney tissue, leading to inflammation and damage to the …
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Mesangial sclerosis refers to scarring or hardening (sclerosis) of a specific area within the kidney known as the mesangium. The mesangium is a support structure within the glomeruli, tiny filters in the kidneys responsible for removing waste and excess fluid from your blood. When the mesangium becomes scarred, it can impair kidney function, leading to …
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Glomerulosclerosis is a condition characterized by scarring or hardening (sclerosis) of the tiny filters in the kidneys known as glomeruli. Normally, these structures help filter waste and excess fluid from your blood. When the glomeruli become scarred, they can’t perform their job effectively, which can eventually lead to impaired kidney function or kidney failure. What …
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What is membranous glomerulonephritis? Membranous glomerulonephritis (also called membranous nephropathy or membranous glomerulopathy) is an autoimmune disease that damages the small filtering units of the kidney called the glomeruli. This damage leads to high levels of protein in the urine. What do the kidneys do? The kidneys are paired bean-shaped organs located just below the …
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Diabetic nephropathy is a kidney disease that can develop in people who have diabetes. It occurs when high blood sugar levels, over a long period of time, damage tiny blood vessels in the kidneys. This damage specifically affects structures called glomeruli, which act as the kidneys’ primary filters. Usually, glomeruli help remove waste and excess …
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