Melanoma is a type of cancer that develops from melanocytes, the cells that give skin its color. Melanocytes are also found in other parts of the body, including the lining of the mouth, nose, and genital and anal areas, and melanoma can begin in any of these locations. KIT testing is a biomarker test performed …
Read More »
CD117 (also known as c-kit or KIT) is a protein found on the surface of certain normal and abnormal cells. It acts like an antenna — receiving signals from the surrounding environment that tell the cell to grow, divide, and survive. In pathology, CD117 is used as an immunohistochemical (IHC) marker, meaning it is detected …
Read More »
A gastrointestinal stromal tumor, or GIST, is a type of cancer that starts in the wall of the digestive tract. The most common locations are the stomach and small intestine, but GISTs can occur anywhere from the esophagus to the rectum. GISTs are distinct from other gastrointestinal cancers because they arise from specialized cells called …
Read More »
