KIT

CD117: Definition

CD117 (also known as c-kit or KIT) is a protein found on the surface of certain normal and abnormal cells. It acts like an antenna — receiving signals from the surrounding environment that tell the cell to grow, divide, and survive. In pathology, CD117 is used as an immunohistochemical (IHC) marker, meaning it is detected …
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Gastrointestinal Stromal Tumor (GIST): Understanding Your Pathology Report

A gastrointestinal stromal tumor, or GIST, is a type of cancer that starts in the wall of the digestive tract. The most common locations are the stomach and small intestine, but GISTs can occur anywhere from the esophagus to the rectum. GISTs are distinct from other gastrointestinal cancers because they arise from specialized cells called …
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