Germinal centers are specialized structures within lymphoid tissues where B cells (a type of white blood cell) mature and differentiate. These centers play an important role in the body’s immune response by helping train B cells to produce antibodies that target specific pathogens. Where are germinal centers normally found? Germinal centers are typically found within …
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Definition: Tingible body macrophages are a type of immune cell found in certain tissues. The term “tingible” refers to their appearance under a microscope, often containing visible remnants of dead cells. These macrophages play an important role in the body’s immune response by engulfing and digesting cellular debris and dead cells. Where are tingible body …
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In pathology, extranodal extension (ENE) refers to the spread of tumour cells beyond the lymph node capsule into the surrounding tissues. This process is observed in various types of cancers that have metastasized to lymph nodes. ENE is considered a marker of aggressive disease and can significantly impact the staging, prognosis, and treatment strategy for …
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What is follicular lymphoma? Follicular lymphoma (FL) is a type of cancer that starts from specialized immune cells called B cells. FL is the second most common lymphoma to affect adults. Where in the body is follicular lymphoma found? FL can start anywhere in the body where B cells gather in large numbers. The most …
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What is a lymph node? Lymph nodes are small organs, located in various locations throughout the body. They are connected to the body and to each other by small channels called lymphatics which contain fluid. Lymph nodes are part of the immune system and their primary function is to ‘sample’ the fluids that circulate around …
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