lymph node

Classic Hodgkin lymphoma

Classic Hodgkin lymphoma (CHL) is a type of cancer that starts in the lymph nodes, which are part of the body’s immune system. It involves a specific type of cell called the Reed-Sternberg cell, which is abnormal and larger than normal lymphocytes (a type of white blood cell). This type of cancer is known for …
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Germinal centers

Germinal centers are specialized structures within lymphoid tissues where B cells (a type of white blood cell) mature and differentiate. These centers play an important role in the body’s immune response by helping train B cells to produce antibodies that target specific pathogens. Where are germinal centers normally found? Germinal centers are typically found within …
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Tingible body macrophages

Definition: Tingible body macrophages are a type of immune cell found in certain tissues. The term “tingible” refers to their appearance under a microscope, often containing visible remnants of dead cells. These macrophages play an important role in the body’s immune response by engulfing and digesting cellular debris and dead cells. Where are tingible body …
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Extranodal extension (ENE)

In pathology, extranodal extension (ENE) refers to the spread of tumour cells beyond the lymph node capsule into the surrounding tissues. This process is observed in various types of cancers that have metastasized to lymph nodes. ENE is considered a marker of aggressive disease and can significantly impact the staging, prognosis, and treatment strategy for …
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Follicular lymphoma

What is follicular lymphoma? Follicular lymphoma (FL) is a type of cancer that starts from specialized immune cells called B cells. FL is the second most common lymphoma to affect adults. Where in the body is follicular lymphoma found? FL can start anywhere in the body where B cells gather in large numbers. The most …
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Lymph nodes

Lymph nodes are small, bean-shaped structures that are part of the body’s lymphatic system. The lymphatic system is a network of tissues and organs, including lymph nodes, that help the body fight infections and other diseases. Each lymph node acts like a filter, trapping germs, cellular debris, foreign particles, and cancer cells. What do lymph …
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