What is HMB-45? HMB-45 (Human Melanoma Black-45) is an antibody that binds to a protein called gp100. This protein is expressed in cells called melanocytes and tumours made up of melanocytes, including melanoma. How is HMB-45 used in pathology? HMB-45 staining is commonly used by pathologists to aid in the diagnosis and classification of tumors …
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What is a congenital nevus? A congenital nevus is a common non-cancerous type of skin tumour made up of melanocytes. Congenital nevi (nevi is the plural of nevus) are more common in people with light-coloured skin. They can be found anywhere on the body, but the most common locations are the trunk and limbs. The …
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What is lentigo maligna? Lentigo maligna is a non-invasive type of skin cancer made up of specialized cells called melanocytes. Another name for lentigo maligna is melanoma in situ. If left untreated, lentigo maligna can turn into an invasive type of skin cancer called lentigo maligna melanoma. Where does lentigo maligna start? Lentigo maligna starts …
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What is melanoma? Melanoma is a type of cancer made of specialized cells called melanocytes. Melanocytes are common in the skin although they can also be found in other parts of the body. Melanocytes produce a chemical called melanin which gives the skin its colour. People with darker skin have more melanin compared to people …
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