What is HMB-45? HMB-45 (Human Melanoma Black-45) is an antibody that binds to a protein called gp100. This protein is expressed in cells called melanocytes and tumours made up of melanocytes, including melanoma. How is HMB-45 used in pathology? HMB-45 staining is commonly used by pathologists to aid in the diagnosis and classification of tumors …
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What is mucosal melanoma? Mucosal melanoma is a type of cancer made up of abnormal melanocytes. In the head and neck, the tumour starts from a thin layer of tissue called mucosa which covers the inside the mouth (oral cavity), nose (nasal cavity), paranasal sinuses (maxillary sinus, ethmoid sinus, frontal sinus, and sphenoid sinus), and …
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What is melanoma in situ? Melanoma in situ is a non-invasive type of skin cancer made up of specialized cells called melanocytes. If left untreated, melanoma in situ can turn into an invasive type of skin cancer called invasive melanoma. Where does melanoma in situ start? Melanoma in situ starts from specialized cells called melanocytes …
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What is lentigo maligna? Lentigo maligna is a non-invasive type of skin cancer made up of specialized cells called melanocytes. Another name for lentigo maligna is melanoma in situ. If left untreated, lentigo maligna can turn into an invasive type of skin cancer called lentigo maligna melanoma. Where does lentigo maligna start? Lentigo maligna starts …
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What is invasive melanoma? Invasive melanoma is a common type of skin cancer made up of cells called melanocytes. This type of skin cancer is more common in people with light skin tones who have a history of long-term sun exposure. Where does invasive melanoma start? Invasive melanoma starts from specialized cells called melanocytes normally …
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