BRCA1 and BRCA2 are tumor suppressor genes. This means they normally help prevent cancer by repairing damaged DNA and regulating cell growth. When either of these genes is mutated (changed), cells are more likely to grow in an uncontrolled way, which can lead to cancer. These mutations can be inherited from a parent and are …
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A mutation is a change in a gene, which is a piece of DNA that provides instructions for how a cell should function. In a molecular pathology report, the word “mutation” means that there has been a genetic change in the tumour’s DNA. Some mutations are harmless, while others can contribute to cancer development or …
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NRAS is a gene that provides instructions for making a protein involved in cell signaling, specifically in controlling cell growth and division. Like other genes in the RAS family, NRAS plays a role in regulating normal cell function. However, when mutations occur in the NRAS gene, the protein it encodes can become overactive, leading to …
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