Salivary gland cancer

Polymorphous adenocarcinoma

Polymorphous adenocarcinoma (previously known as polymorphous low-grade adenocarcinoma) is a type of cancer that arises in the salivary glands. It typically occurs in the minor salivary glands found throughout the mouth and throat. This tumour is most commonly seen in the palate, but it can also occur in other areas such as the lip, buccal mucosa …
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Epithelial-myoepithelial carcinoma

Epithelial-myoepithelial carcinoma (EMC) is a type of salivary gland cancer. The tumour is described as a biphasic salivary gland neoplasm because it is made up of two populations of cells: ductal (luminal) cells and myoepithelial (abluminal) cells. The most common location for epithelial-myoepithelial carcinoma is the parotid gland, although the tumour can be found in …
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Secretory carcinoma of the salivary glands

What is secretory carcinoma of the salivary glands? Secretory carcinoma is a relatively uncommon type of salivary gland cancer. It is characterized by a genetic change involving the genes ETV6, RET, or NTRK3. This genetic change results in a combination or fusion of two of the three genes. A similar tumour can be found in …
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Acinic cell carcinoma

Background: Acinic cell carcinoma is a type of cancer that primarily affects the salivary glands. There are three major pairs of salivary glands: the parotid glands, the submandibular glands, and the sublingual glands, along with hundreds of minor salivary glands located throughout the mouth and throat. Acinic cell carcinoma can develop in any of these …
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Hyalinizing clear cell carcinoma

What is hyalinizing clear cell carcinoma? Hyalinizing clear cell carcinoma (HCCC) is a slow-growing type of head and neck cancer. A genetic alteration involving the EWSR1 gene is found in most HCCCs. Where is hyalinizing clear cell carcinoma normally found? Most HCCCs tumours arise from minor salivary glands which are normally found in the lip, …
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Salivary duct carcinoma

What is salivary duct carcinoma? Salivary duct carcinoma is a type of salivary gland cancer. Salivary duct carcinoma is an aggressive cancer that often spreads into the tissue surrounding the salivary gland and to other organs such as lymph nodes and the lungs. Where in the body is salivary duct carcinoma normally found? The most …
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Adenoid cystic carcinoma

Adenoid cystic carcinoma (ACC) is a slow-growing but locally aggressive type of cancer most commonly found in one of the major salivary glands, such as the parotid, submandibular, or sublingual gland. Other possible locations include the skin, lungs, breasts, and prostate gland. Adenoid cystic carcinoma grows slowly but spreads widely into surrounding tissues. However, unlike …
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Mucoepidermoid carcinoma

What is mucoepidermoid carcinoma? Mucoepidermoid carcinoma (MEC) is a type of salivary gland cancer. The most common location for mucoepidermoid carcinoma is the parotid gland, however, any of the major or minor salivary glands can be affected. Although rare, this type of tumour can also be found in other organs such as the lungs and …
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