sarcoma

Myeloid sarcoma

Myeloid sarcoma is a type of cancer that develops from a group of blood-forming cells called myeloid blasts. These cells normally grow and mature in the bone marrow, which is the spongy tissue inside our bones. In myeloid sarcoma, abnormal myeloid blasts form a mass or tumour outside the bone marrow. This tumour can grow …
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Liposarcoma

Liposarcoma is a type of cancer that develops from fat cells. It is classified as a soft tissue sarcoma, which means it arises in the connective tissues of the body. Liposarcomas are most commonly found in areas where fat is normally present, such as the abdomen or limbs. While liposarcoma is rare, it is one …
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STAT6

STAT6 (Signal Transducer and Activator of Transcription 6) is a protein found in cells. It plays a key role in transmitting signals from outside a cell to its nucleus, where genetic material is stored. This signaling helps regulate how cells grow, divide, and respond to their environment. STAT6 is especially important in controlling immune system …
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Spindle cell/sclerosing rhabdomyosarcoma

Spindle cell/sclerosing rhabdomyosarcoma is a rare type of cancer that starts in skeletal muscle tissue, which is responsible for voluntary movements. It can affect people of all ages, but the features of this cancer can vary between children and adults. This type of rhabdomyosarcoma is named for the unique appearance of its cells under the …
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Pleomorphic rhabdomyosarcoma

Pleomorphic rhabdomyosarcoma is a rare type of cancer that starts in the skeletal muscle tissue, the muscle responsible for voluntary movements like walking or lifting objects. This cancer is called “pleomorphic” because the tumour cells can take on many different shapes and sizes. It is most commonly found in adults, especially in the arms, legs, …
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FNCLCC (Fédération Nationale des Centres de Lutte Contre le Cancer)

The FNCLCC (Fédération Nationale des Centres de Lutte Contre le Cancer) is the most common grading system doctors use to evaluate soft tissue sarcomas, which are cancers that start in tissues like muscles, fat, or blood vessels. This grading system helps doctors assess how aggressive (fast-growing) the tumour is, guiding treatment decisions and helping predict …
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Pleomorphic liposarcoma

Background: Pleomorphic liposarcoma is a rare and aggressive type of cancer that develops from fat cells. Unlike well differentiated liposarcoma, which still resembles normal fat tissue, pleomorphic liposarcoma is made up of very abnormal cells that look nothing like normal fat cells. This type of cancer can grow quickly and has a higher risk of …
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Rhabdoid

In pathology, the term “rhabdoid” is used to describe tumour cells that resemble rhabdomyoblasts, which are immature skeletal muscle cells. However, these cells are not true rhabdomyoblasts and the tumours they arise in are not related to muscle tissue. Rhabdoid cells can be seen in a wide variety of tumour types and the presence of …
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Low grade fibromyxoid sarcoma

Low grade fibromyxoid sarcoma (also known as Evan’s tumour) is a rare type of soft tissue cancer. As its name suggests, low grade fibromyxoid sarcoma is typically considered a low grade sarcoma, meaning it tends to grow and spread more slowly compared to high grade tumours. However, it has a potential for late recurrence and …
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Alveolar soft part sarcoma

Background: Alveolar soft part sarcoma is a rare type of cancer that typically starts in the body’s soft tissues, including muscles, fat, and connective tissues. Despite its name, alveolar soft part sarcoma does not start in the lung’s alveolar structures, as one might think from the word “alveolar.” Instead, it gets its name from the …
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