S100 is a protein normally found inside many different types of cells in the human body. It plays a role in various cellular processes, such as cell growth and communication. Pathologists can use special tests to detect this protein in tissues, which can help them diagnose certain types of tumours and other medical conditions. What …
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Fluorescence in situ hybridization (FISH) is a laboratory test used in pathology to detect and localize the presence or absence of specific DNA sequences on chromosomes. It works by using fluorescent probes that bind to only those parts of the chromosome that match or are complementary to the probe. It is commonly used in the …
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Immunohistochemistry (IHC) is a widely used laboratory test that involves the use of antibodies to detect specific antigens (proteins) in cells within tissue sections. Pathologists use this test to see the distribution and localization of specific proteins within different parts of a tissue, thereby providing valuable diagnostic, prognostic, and predictive information. How does immunohistochemistry work? …
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