TFE3

Alveolar soft part sarcoma

Background: Alveolar soft part sarcoma is a rare type of cancer that typically starts in the body’s soft tissues, including muscles, fat, and connective tissues. Despite its name, alveolar soft part sarcoma does not start in the lung’s alveolar structures, as one might think from the word “alveolar.” Instead, it gets its name from the …
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Xp11 translocation renal cell carcinoma

What is Xp11 translocation renal cell carcinoma? Xp11 translocation renal cell carcinoma (RCC) is a type of kidney cancer. It is called ‘Xp11 translocation’ because the tumour cells contain a genetic alteration involving the TFE3 gene which is located in the p11 region of chromosome X. Another name for this type of cancer is TFE3-rearranged …
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