translocation

Translocation

A translocation is a specific type of genetic change where a piece of one chromosome breaks off and attaches to another chromosome. Chromosomes are structures inside your cells that carry DNA, which contains the instructions your body needs to grow and function. When pieces of chromosomes switch places, they create new combinations of genetic material. …
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Xp11 translocation renal cell carcinoma

What is Xp11 translocation renal cell carcinoma? Xp11 translocation renal cell carcinoma (RCC) is a type of kidney cancer. It is called ‘Xp11 translocation’ because the tumour cells contain a genetic alteration involving the TFE3 gene which is located in the p11 region of chromosome X. Another name for this type of cancer is TFE3-rearranged …
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TFE3-rearranged renal cell carcinoma

What is TFE3-rearranged renal cell carcinoma? TFE3-rearranged renal cell carcinoma (RCC) is a type of kidney cancer. It is called ‘TFE3-rearranged’ because the tumour cells contain a genetic alteration involving the TFE3 gene. Another name for this type of cancer is Xp11 translocation renal cell carcinoma. What causes TFE3-rearranged renal cell carcinoma? This type of …
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