I-ovarian fibroma

NguJason Wasserman MD PhD FRCPC
June 7, 2023

Iyini i-ovarian fibroma?

I-Ovarian fibroma uhlobo olungenalo umdlavuza lwe-ovarian tumor. Ikhula kusukela kumaseli e-stromal ngokuvamile atholakala ngaphakathi kwe-ovary. Lezi zimila zingahluka ngosayizi ukusuka ngaphansi kuka-1.0 cm ukuya ngaphezulu kuka-20 cm.

Yiziphi izimpawu ze-ovarian fibroma?

Iningi lama-ovarian fibromas alibangeli noma yiziphi izimpawu futhi isimila sitholakala ngokuzenzakalelayo lapho izithombe ze-pelvis zenziwa ngezinye izizathu noma lapho i-ovary ikhishwa ngenxa yezinye izizathu. Ama-ovarian fibromas amakhulu angabangela izimpawu ezinjengobuhlungu noma ukucindezela kwesisu.

Izazi ze-pathologists zikwenza kanjani ukuxilongwa kwe-ovarian fibroma?

Ukuxilongwa kwe-ovarian fibroma ngokuvamile kwenziwa ngemva kokuba i-ovary yonke isusiwe ngokuhlinzwa futhi ithunyelwe kudokotela wezifo ukuze ahlolwe ngaphansi kwe-microscope.

Ibukeka kanjani i-ovarian fibroma ngaphansi kwe-microscope?

Nge-Microscopically, isimila sakhiwe amangqamuzana amade amancane abizwa ngokuthi amaseli okuphotha. Amaseli okuphotha ngokuvamile ahlelwa ngamaqembu amagatsha abizwa ngokuthi ama-fascicles futhi azungezwe izicubu ezixhumene eziminyene ezingase zichazwe njenge-hyalinized noma i-fibrotic. Inombolo encane yamaseli e-tumor ahlukanisayo abizwa izibalo ze-mitotic kungase futhi kubonakale. Izimila ezinkulu noma lezo esezinesikhathi eside zikhona zingase zibe nochungechunge lwezinguquko eziwohlokayo ezihlanganisa ukopha (ukopha ku-tumor) kanye nohlobo lwe-infarct. i-necrosis (ukufa kwamangqamuzana ngenxa yokuncipha kokugeleza kwegazi). Izimila ezinobuningi obukhulu bamaseli e-tumor (inani lamaseli endaweni ethile yezicubu) zibizwa ama-cellular fibroma kuyilapho lezo ezibonisa ukwanda kwenani lezibalo ze-mitotic zibizwa i-mitotically active cell fibromas.

I-pathologist yakho ingenza ukuhlolwa okubizwa i-immunohistochemistry ukuqinisekisa ukuxilongwa. Lapho kwenziwa i-immunohistochemistry, amangqamuzana e-tumor ku-ovarian fibroma ngokuvamile aba ne-inhibin, i-calretinin, i-WT1, nama-hormone receptors. i-estrogen receptor (ER) futhi i-progesterone receptor (PR).