Use your browser's print dialog to print or save as PDF. This page is formatted for easy reading on paper.
MyPathologyReport Printed: October 6, 2026

Mesothelial Cells: Definition

What are mesothelial cells?

Mesothelial cells are the cells that cover our internal organs such as our lungs, liver, stomach, and colon. They form a barrier on the outside of these organs that protect the organs from injury.

These cells respond to injury or damage by becoming larger. Pathologists call these cells reactive mesothelial cells. Nearby cancer cells also cause these cells to become reactive.

Tumours made of mesothelial cells

Mesothelioma is a type of cancer that starts from mesothelial cells. This type of cancer is most common around the lungs, but it can also start in the abdomen or pelvis. Another name for mesothelioma is malignant mesothelioma.