Ki-67

Ki-67 iphrotheni etholakala ku nucleus yamaseli, okuyisikhungo sokulawula ngaphakathi kweseli ngalinye. Le phrotheni ivela lapho amaseli elungiselela ukuhlukanisa nokudala amaseli amasha, inqubo eyaziwa ngokuthi i-mitosis noma ukuhlukaniswa kwamaseli. Le phrotheni ayikho kumaseli aphumule - lawo angekho ohlelweni lokuhlukanisa. Odokotela bezifo benza ukuhlolwa okubizwa ngokuthi i-immunohistochemistry (IHC) ukubona amaseli eveza le phrotheni (lawa maseli abizwa ngokuthi i-positive noma i-reactive). Ngokulinganisa amazinga e-Ki-67, izazi zezifo zingakala ukuthi amaseli ahlukana kangakanani, anikeze imininingwane mayelana nokuziphatha kokukhula kwezicubu, ikakhulukazi ezimila.

Inkomba yokulebula ye-Ki-67

The Inkomba yokulebula ye-Ki-67 (LI) iphesenti lamaseli aveza i-Ki-67. Ngamanye amazwi, iphesenti lawo wonke amaseli angahlukana. Izazi zezifo zivame ukulinganisa inkomba yokulebula izimila ukuze babasize banqume ukuthi isimila sikhona yini benign (okungewona umdlavuza) noma okubi (umdlavuza). Umdlavuza kungenzeka ukuthi ube nenkomba ephezulu yokulebula. Inkomba yokulebula iphinde isetshenziselwe ukunikeza ulwazi mayelana nendlela isimila esizoziphatha ngayo noma ukuthi sizosabela kanjani ekwelashweni.

Mayelana nalesi sihloko

Lesi sihloko sabhalwa odokotela ukuze bakusize ufunde futhi uqonde umbiko wakho we-pathology. Xhumana nathi uma unemibuzo mayelana nalesi sihloko noma umbiko wakho we-pathology. Ukuze uthole isingeniso esiphelele sombiko wakho we-pathology, funda lesi sihloko.

Izihloko ezihlobene

Umfanekiso weMitotic

Umfanekiso we-Atypical we-mitotic

Mitosis

Ezinye izinsiza eziwusizo

I-atlas ye-pathology