I-Cellular fibroma ye-ovary

nguJason Wasserman MD PhD FRCPC
Mashi 7, 2023

Iyini i-fibroma yeselula?

I-cell fibroma wuhlobo olungenawo umdlavuza lwe-ovarian tumor. Iqala kusuka kumaseli e-stromal ngokuvamile atholakala ngaphakathi kwe-ovary. Lezi zimila zingahluka ngosayizi ukusuka ngaphansi kuka-1.0 cm ukuya ngaphezulu kuka-20 cm. Ibizwa ngokuthi i-'cellular' fibroma ngoba ukuminyana kwamaseli wesimila (inani lamaseli endaweni enikeziwe) kuphezulu uma kuqhathaniswa navamile. i-ovarian fibroma.

Yiziphi izimpawu ze-fibroma yeselula ye-ovary?

Ama-fibromas amaselula amakhulu angabangela izimpawu ezinjengobuhlungu noma ukucindezela kwesisu. Amathumba amancane angeke abangele noma yiziphi izimpawu isimila singatholakala ngengozi (ngengozi) lapho ukuhlolwa kwesithombe njenge-ultrasound noma i-CT scan ye-pelvis kwenziwa ngezinye izizathu.

Kwenziwa kanjani ukuxilongwa kwe-cell fibroma?

Ukuxilongwa kwe-cell fibroma ngokuvamile kwenziwa ngemva kokuba i-ovary yonke isusiwe ngokuhlinzwa futhi ithunyelwe kudokotela wezifo ukuze ahlolwe ngaphansi kwe-microscope. Ngokwe-Microscopically, isimila sakhiwe amangqamuzana amade amancane abizwa ngokuthi amaseli okuphotha. Amaseli okuphotha ngokuvamile ahlelwa ngamaqembu amagatsha abizwa ngokuthi ama-fascicles futhi azungezwe izicubu ezixhumene eziminyene ezingase zichazwe njenge-hyalinized noma i-fibrotic. Ukuminyana kwamaseli spindle (inani lamaseli endaweni ethile yethishu) kuphezulu ku-fibroma yeselula uma kuqhathaniswa nokuvame kakhulu. i-ovarian fibroma. Inombolo encane yamaseli e-tumor ahlukanisayo abizwa izibalo ze-mitotic kungase futhi kubonakale.

Izimila ezibonisa ukwanda kwenani lezibalo ze-mitotic zibizwa i-mitotically active cell fibromas. Izimila ezinkulu noma lezo esezinesikhathi eside zikhona zingase zibe nochungechunge lwezinguquko eziwohlokayo ezihlanganisa ukopha (ukopha esimila) kanye nohlobo lwe-infarct. i-necrosis (ukufa kwamangqamuzana ngenxa yokuncipha kokugeleza kwegazi).

I-pathologist yakho ingenza ukuhlolwa okubizwa i-immunohistochemistry ukuqinisekisa ukuxilongwa. Lapho kwenziwa i-immunohistochemistry, amangqamuzana ethumba ku-fibroma yeselula avame ukuba ne-inhibin, i-calretinin, i-WT1, nama-hormone receptors. i-estrogen receptor (ER) futhi i-progesterone receptor (PR).