Pathology dictionary -
Stroma is the connective tissue that provides our organs with structural support. Like other types of tissue, stroma reacts in response to changes in its environment. Pathologists use the word desmoplasia (or desmoplastic) to to describe the way stroma looks under the microscope after it has come in contact with cancer cells.
Desmoplasia allows pathologists to find even small groups of cancer cells. Desmoplasia can also be used to tell the difference between early or non-invasive cancer and invasive cancer because cancer because desmoplasia is usually only seen with invasive cancer.