September 24, 2023
CD3 is a protein that is normally made by two types of specialized immune cells, T cells and NK cells. Most lymphomas that start from T and NK cells, including peripheral T cell lymphoma, anaplastic large cell lymphoma, and extranodal NK/T cell lymphoma, also make CD3.
Two common tests used to look for CD3 in a tissue sample are immunohistochemistry and flow cytometry. Immunohistochemistry is performed on a tissue sample attached to a glass slide. The slide is then examined under a microscope. Flow cytometry uses a special machine to count and analyze the number of cells in a tissue sample that were making CD3.
Doctors wrote this article to assist you in reading and comprehending your pathology report. Feel free to reach out to us with any questions about this article or your pathology report. To get a comprehensive introduction to your pathology report, read this article.