In-transit metastasis is a group of tumour cells found within the skin or soft tissue at least 20 mm from the original tumour. The term ‘in-transit’ is used because the tumour cells are found in between the original tumour and the first lymph nodes that drain that area of the body.
Pathologists typically use the term in-transit metastasis to describe the movement of tumour cells in melanoma, a type of skin cancer. In melanoma, pathologists look for in-transit metastases to determine the pathologic cancer stage (pTNM).
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Atlas of Pathology
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