Lymphatic invasion describes a situation where cancer cells have moved from the primary tumor into tiny channels in the body known as lymphatic vessels. These vessels are part of the lymphatic system, a network that helps maintain fluid balance in the body and plays a crucial role in fighting infections. When cancer cells enter these lymphatic vessels, they have the potential to travel to nearby lymph nodes and possibly to other areas of the body.
Lymphatic invasion means cancer cells have entered the lymphatic vessels near the original tumor. However, it does not always mean the cancer has spread to other parts of the body. It does indicate a higher chance that cancer cells may have reached nearby lymph nodes or other tissues, raising concerns about the possibility of cancer spreading in the future.
If your pathology report states that lymphatic invasion is “positive” or “present,” it means that cancer cells have been identified inside the lymphatic vessels under the microscope. This finding is significant because it suggests an increased risk of cancer cells traveling to nearby lymph nodes or elsewhere. Knowing that lymphatic invasion is present helps your medical team decide on the best treatment plan, including the extent of surgery, and whether additional treatments such as chemotherapy or radiation therapy might be beneficial.
Lymphatic invasion specifically refers to cancer cells entering lymphatic vessels, which carry lymph fluid throughout the body and toward lymph nodes. In contrast, lymphovascular invasion is a broader term used when cancer cells are found within either lymphatic vessels or blood vessels. Both terms indicate a higher risk of cancer spreading beyond its original location, but lymphovascular invasion highlights that the cancer cells could use either lymphatic channels or blood vessels to spread. This distinction can influence treatment decisions and patient monitoring plans.