by Jason Wasserman MD PhD FRCPC
August 25, 2022
Plantar fibromatosis is a non-cancerous growth found on the flexor (sole) side of the foot. Another name for this condition is Ledderhose disease.
No. Plantar fibromatosis is a non-cancerous growth.
These two conditions are very similar. However, palmar fibromatosis involves the hand while plantar fibromatosis involves the foot.
In adults, plantar fibromatosis may be associated with diabetes, cigarette smoking, alcoholism, and repetitive trauma to the foot. However, at present, the cause of plantar fibromatosis remains unknown.
For most people, plantar fibromatosis develops slowly over time with very few symptoms. Later, the disease may cause pain in the foot, especially when standing for long periods of time.
Your doctor may suspect that you have plantar fibromatosis after talking to you and examining your feet. The diagnosis can also be made after the abnormal tissue is surgically removed and sent to a pathologist for examination under the microscope.
When examined under the microscope, plantar fibromatosis is made up of specialized cells called fibroblasts or myofibroblasts surrounded by a type of connective tissue called collagen. Most pathology reports use the term spindle cells to describe these cells because they are long and thin. The number of both fibroblasts and myofibroblasts is greater early on and decreases over time.