AE1/AE3 are a pair of antibodies that recognize multiple cytokeratins, intermediate filament proteins found in epithelial cells. Cytokeratins are normally located in the cytoplasm (body) of the epithelial cell. Pathologists perform a test called immunohistochemistry to stain tissues for AE1/AE3 and the pattern and intensity of staining can help identify the presence of epithelial cells …
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