Mesothelial proliferation is a term used by pathologists to describe an increase in the number of mesothelial cells. Mesothelial cells form a thin layer that lines the membranes around the lungs (pleura), abdomen (peritoneum), heart (pericardium), and testis (tunica vaginalis). A mesothelial proliferation can be benign (noncancerous) or, less commonly, part of a malignant (cancerous) process …
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Mesothelial hyperplasia is a noncancerous condition in which the cells that line the membranes around the lungs, abdomen, heart, or testis—called mesothelial cells—begin to grow or multiply more than usual. These membranes are known as the pleura (around the lungs), peritoneum (around the abdominal organs), pericardium (around the heart), and tunica vaginalis (around the testis). …
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The term atypical mesothelial proliferation is used when a pathologist sees mesothelial cells—the cells that line the membranes covering the lungs (pleura), abdomen (peritoneum), heart (pericardium), or testis (tunica vaginalis)—that look abnormal (atypical) under the microscope. This finding means that the pathologist sees some worrisome changes in how the mesothelial cells look or grow, but …
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An excisional biopsy is a type of surgical procedure in which the entire abnormal area of tissue is removed so it can be examined under a microscope by a pathologist. Unlike other types of biopsies that only take a small sample, an excisional biopsy removes the whole lump, lesion, or suspicious area. This enables the …
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A bone marrow biopsy is a medical procedure in which a small sample of bone marrow is taken so that it can be examined under a microscope by a pathologist. The bone marrow is the soft tissue found inside bones, and it is where most of your blood cells are made. By looking at a …
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A liquid biopsy is a medical test that detects signs of disease, such as cancer, in a sample of body fluid—most often blood. Unlike a traditional biopsy, which involves removing a small tissue sample with a needle or during surgery, a liquid biopsy is minimally invasive and can be done with a simple blood draw. …
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Pemphigus is a group of rare autoimmune diseases that affect the skin and mucous membranes (the moist surfaces inside your mouth, nose, throat, and genitals). The outer layer of these tissues is made of keratinocytes, which are flat cells arranged like tiles on a roof. In pemphigus, the immune system produces antibodies that target specific …
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Melanosis coli is a harmless condition that affects the large intestine (colon). In this condition, the lining of the colon turns dark brown or black due to a buildup of a pigment called lipofuscin. This pigment develops within cells that line the inside surface of the colon. Melanosis coli is noncancerous and typically related to …
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Atypical small acinar proliferation (ASAP) is a term pathologists use when examining a prostate biopsy under a microscope. It describes a small group of atypical prostate glands that could represent reactive features, benign (noncancerous) entities, or low grade prostate cancer. The microscopic features of ASAP are insufficient to establish a definitive cancer diagnosis, although it …
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Poorly differentiated carcinoma is a type of cancer made up of cells that line the surfaces of organs. Differentiation refers to the degree to which cancer cells resemble normal cells from the tissue in which they originated. When cancer is poorly differentiated, the tumour cells have lost many of the normal structures and features, making …
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