BRCA1 and BRCA2 are genes whose normal job is to repair damaged DNA and prevent cells from becoming cancerous. When one of these genes carries a harmful mutation, meaning a change in the gene’s DNA sequence that stops it from working the way it should, that protective function is lost, and the risk of developing …
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If your pathology report or treatment records mention homologous recombination deficiency, or HRD, this refers to the result of a test that measures whether the cells in your tumour can repair a particular type of DNA damage. In ovarian cancer, HRD testing has become an important part of treatment planning because tumours that cannot perform …
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If your pathology report or genetic test results mention BRCA1 or BRCA2, these refer to two genes that play a critical role in repairing damaged DNA. In ovarian cancer, BRCA testing is one of the most important molecular tests performed — not just because a mutation in either gene helps predict how the cancer will …
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BRCA1 and BRCA2 are genes that normally protect cells from becoming cancerous. Their job is to repair damaged DNA and keep cell division under control. When one of these genes carries a harmful mutation — a change that prevents the gene from working properly — that protective function is lost, and the risk of developing …
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BRCA1 and BRCA2 are tumor suppressor genes. This means they normally help prevent cancer by repairing damaged DNA and regulating cell growth. When either of these genes is mutated (changed), cells are more likely to grow in an uncontrolled way, which can lead to cancer. These mutations can be inherited from a parent and are …
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