cancer marker

What is CD10?

CD10 is a protein found on the surface of specific normal cells in the body. In pathology, CD10 is an immunohistochemical marker, meaning it can be highlighted in tissue samples using a specialized laboratory stain. Pathologists use CD10 to identify which cell types are present in a biopsy and to better classify diseases such as …
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AMACR: Definition

AMACR (alpha-methylacyl-CoA racemase) is a protein found inside certain cells that helps the body break down specific types of fats. In pathology, AMACR is important because cancer cells in the prostate and several other organs tend to produce much larger amounts of this protein than normal, healthy cells do. Pathologists use an AMACR test to …
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Racemase: Definition

Racemase, also known as alpha-methylacyl-CoA racemase (AMACR) or P504S, is a protein produced by certain types of cells in the body. Pathologists use special tests to look for racemase in tissue samples because its presence or absence can help them make a diagnosis, particularly when examining conditions affecting the prostate gland. Although racemase is naturally …
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What is BAP1?

BAP1 stands for BRCA1 Associated Protein-1, a protein found inside cells throughout the body. It is located on chromosome 3 and acts as a tumor suppressor, meaning it helps prevent cells from growing uncontrollably and turning into cancer. Loss of BAP1 activity or expression in cells is often associated with certain aggressive cancers and can …
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SATB2: Definition

SATB2 (Special AT-rich Sequence-Binding Protein 2) is a protein that plays an important role in controlling how specific genes are turned on and off. This protein helps cells grow and function normally by organizing the genetic information inside them. SATB2 is like a “manager”, ensuring specific genes work as needed. What types of normal cells …
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