cancer report

Lymph Nodes in Your Pathology Report: What the Numbers and Terms Mean

Lymph nodes are small, bean-shaped organs that filter tissue fluid and help the body fight infection. Cancer cells can travel through lymphatic channels and settle in nearby lymph nodes. For that reason, lymph nodes are often removed during cancer surgery and examined by a pathologist. A lymph node may also be removed on its own …
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Tumour Mutational Burden

Tumour mutational burden — usually abbreviated as TMB — is a measurement of how many genetic mutations are present in a tumour. The more mutations a cancer carries, the more it tends to look different from normal cells to the immune system. Because immunotherapy drugs work by helping the immune system find and attack cancer, …
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MMR-deficient (dMMR): Definition

MMR-deficient, often written as dMMR, means that one or more of the proteins responsible for repairing mistakes in a cell’s DNA are missing or not working properly. When these repair proteins are lost, errors in DNA can accumulate over time, contributing to the development of cancer. Finding dMMR in a tumour has important implications for …
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Understanding Your Breast Biopsy Pathology Report

A breast biopsy is a procedure in which a small amount of tissue is removed from the breast and sent to a pathology laboratory for examination. It is the only way to know for certain whether a breast abnormality is cancerous, precancerous, or benign. If you have received a breast biopsy pathology report, you may …
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