In pathology, dedifferentiation describes a process where mature, specialized cells change back (revert) to a less specialized, more primitive form. This is commonly seen in cancer, where tumour cells that were initially more mature and less aggressive become less mature and more aggressive. When cells become dedifferentiated, they tend to grow more rapidly and lose …
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Dedifferentiated chondrosarcoma is an aggressive type of cancer made up of tumour cells that resemble cartilage. The tumour is called ‘dedifferentiated’ because it develops from within a more well-differentiated type of cartilage cancer called conventional chondrosarcoma. What are the symptoms of dedifferentiated chondrosarcoma? Symptoms of dedifferentiated chondrosarcoma include pain and swelling over the involved bone. …
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