Mismatch repair (MMR) testing is one of the most important tests performed on endometrial cancer, the cancer that starts in the lining of the uterus. Every newly diagnosed endometrial cancer should be tested for this biomarker. The result tells your doctor whether the cancer’s internal DNA repair system is working properly. If it isn’t — …
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MMR-deficient, often written as dMMR, means that one or more of the proteins responsible for repairing mistakes in a cell’s DNA are missing or not working properly. When these repair proteins are lost, errors in DNA can accumulate over time, contributing to the development of cancer. Finding dMMR in a tumour has important implications for …
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Mismatch repair (MMR) and microsatellite instability (MSI) testing are among the most important biomarker tests performed on colorectal cancers. Every colorectal cancer — whether found on a biopsy or in a surgical specimen — should be tested for this biomarker. The results tell your doctor whether your cancer’s DNA repair system is working normally or …
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