A POLE mutation is one of the most important findings a pathologist can report in an endometrial cancer — not because it signals danger, but because it signals the opposite. Endometrial cancers with a pathogenic POLE mutation belong to the molecular group with the best prognosis of all four endometrial cancer subtypes. These cancers rarely …
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Endometrial endometrioid carcinoma is a cancer that begins in the endometrium, the inner lining of the uterus. It is by far the most common type of endometrial cancer, and it most often affects women after menopause. Most of these cancers are found early, while still confined to the uterus, because they cause bleeding that prompts …
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Endometrioid carcinoma of the ovary is a type of ovarian cancer whose cells resemble the cells of endometrioid carcinoma of the uterus when examined under the microscope. It develops from epithelial cells and accounts for about 10% of all ovarian carcinomas. Unlike the more common high-grade serous carcinoma, most endometrioid carcinomas of the ovary are …
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