A POLE mutation is one of the most important findings a pathologist can report in an endometrial cancer — not because it signals danger, but because it signals the opposite. Endometrial cancers with a pathogenic POLE mutation belong to the molecular group with the best prognosis of all four endometrial cancer subtypes. These cancers rarely …
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Endometrial endometrioid carcinoma is a type of cancer that begins in the endometrium, the inner lining of the uterus. It is the most common type of endometrial cancer and most often affects women after menopause. This type of cancer frequently develops from a precancerous condition called atypical endometrial hyperplasia, in which the endometrial cells show …
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Endometrioid carcinoma of the ovary is a type of ovarian cancer whose cells resemble the cells of endometrioid carcinoma of the uterus when examined under the microscope. It develops from epithelial cells and accounts for about 10% of all ovarian carcinomas. Unlike the more common high-grade serous carcinoma, most endometrioid carcinomas of the ovary are …
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