gastric cancer

Hereditary diffuse gastric and lobular breast cancer syndrome (CDH1)

CDH1 is a gene that carries the instructions for making E-cadherin, a protein that holds neighboring cells together. When a change in this gene is inherited, it causes a condition that raises the lifetime risk of two specific cancers: diffuse gastric cancer, a type of stomach cancer, and lobular breast cancer. The condition is called …
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Claudin 18.2 in Gastric and Gastroesophageal Junction Cancer

Claudin 18.2 is a protein that helps cells in the lining of the stomach stick tightly together. It is one of the newest biomarkers in adenocarcinoma of the stomach (gastric cancer) and adenocarcinoma of the esophagus, including cancer of the gastroesophageal junction (the area where the esophagus meets the stomach), because it can be targeted …
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Adenocarcinoma of the Stomach: Understanding Your Pathology Report

Adenocarcinoma is the most common type of stomach cancer, accounting for roughly 90% to 95% of all cases. It begins in the glandular cells that line the inside of the stomach, the cells that normally produce mucus and digestive juices. In adenocarcinoma, these cells grow in an uncontrolled way and form a tumor that can …
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