SDH-deficient gastrointestinal stromal tumour is a rare type of gastrointestinal stromal tumour (GIST) that almost always develops in the stomach. Like other GISTs, it arises from specialized cells in the wall of the digestive tract that help regulate gut motility. What makes this tumour different is that it is caused by a problem in a …
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DOG1 (Discovered on GIST-1) is a protein found on the surface of certain cells. It is commonly used in pathology to identify specific types of tumours. DOG1 was first identified in gastrointestinal stromal tumours (GISTs), but it can also be found in other normal tissues and tumours. What is the function of DOG1? Although DOG1’s …
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A gastrointestinal stromal tumour, or GIST, is a type of cancer that starts in the digestive tract. The most common places for GISTs to develop are the stomach and small intestine, but they can occur anywhere along the digestive tract. GISTs are different from other types of tumours because they start in special cells called …
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