SDH-deficient gastrointestinal stromal tumor (GIST) is a rare and distinct subtype of gastrointestinal stromal tumor that almost always develops in the stomach. Like other GISTs, it arises from specialized cells in the wall of the digestive tract that help regulate gut movement. What sets this tumor apart is that it is caused by a problem …
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DOG1 (Discovered on GIST-1) is a protein found on the surface of certain cells. It is commonly used in pathology to identify specific types of tumours. DOG1 was first identified in gastrointestinal stromal tumours (GISTs), but it can also be found in other normal tissues and tumours. What is the function of DOG1? Although DOG1’s …
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A gastrointestinal stromal tumor, or GIST, is a type of cancer that starts in the wall of the digestive tract. The most common locations are the stomach and small intestine, but GISTs can occur anywhere from the esophagus to the rectum. GISTs are distinct from other gastrointestinal cancers because they arise from specialized cells called …
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