HER2 (human epidermal growth factor receptor 2) is a protein found on the surface of cells that acts like an antenna, receiving signals that tell the cell to grow and divide. In normal breast tissue, HER2 is present in small amounts and plays a controlled role in cell growth. In some breast cancers, the gene …
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Triple-negative breast cancer is a term used to describe breast cancers that do not show expression of three common markers: Estrogen receptor (ER). Progesterone receptor (PR). HER2 (also called ERBB2). These three markers are important because they are often used to guide treatment. Breast cancers that are ER-positive, PR-positive, or HER2-positive can be treated with …
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