Liposarcoma is a type of cancer that develops from fat cells. It is classified as a soft tissue sarcoma, which means it arises in the connective tissues of the body. Liposarcomas are most commonly found in areas where fat is normally present, such as the abdomen or limbs. While liposarcoma is rare, it is one …
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What is MDM2? MDM2 is a gene that promotes cell division (the creation of new cells). Normal cells and those in non-cancerous tumours have two copies of the MDM2 gene. In contrast, cancerous tumours such as atypical lipomatous tumour/well differentiated liposarcoma have more than two copies of the MDM2 gene. How do pathologists test for …
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An atypical lipomatous tumor (ALT) is a slow-growing, low-grade type of sarcoma — a cancer that arises from fat cells. ALT is closely related to well-differentiated liposarcoma; in fact, both names refer to the same underlying tumor. The term ALT is used when the tumor arises in a location where complete surgical removal is achievable, …
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Well differentiated liposarcoma is a type of sarcoma, which is a cancer that starts in connective tissues such as fat, muscle, or bone. In this tumor, the cancer cells come from fat cells (adipocytes). Under the microscope, the cells still resemble fat cells, but they appear more abnormal in size and shape than normal fat …
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Dedifferentiated liposarcoma is an aggressive type of sarcoma — a cancer that arises from fat cells. It is called dedifferentiated because it develops from within a less aggressive fatty tumor called well-differentiated liposarcoma (also known as atypical lipomatous tumor). During this transformation, a portion of the tumor’s fat cells are replaced by a completely different …
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What is an intramuscular lipoma? Intramuscular lipomas are non-cancerous tumours made up of fat. These tumours develop deep inside a muscle and they may feel like a lump. Often, intramuscular lipomas are not well separated from the surrounding normal muscle which can make it challenging for your surgeon to remove the tumour completely. What is …
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A lipoma is a benign (non-cancerous) tumour made up of mature fat cells, also called adipocytes. Lipomas are part of a group of tumours known as mesenchymal tumours, which arise from connective tissues such as fat, muscle, or fibrous tissue. Lipoma is the most common type of soft tissue tumour in adults. Lipomas grow slowly …
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