MDM2

MDM2

What is MDM2? MDM2 is a gene that promotes cell division (the creation of new cells). Normal cells and those in non-cancerous tumours have two copies of the MDM2 gene. In contrast, cancerous tumours such as atypical lipomatous tumour/well differentiated liposarcoma have more than two copies of the MDM2 gene. How do pathologists test for …
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Atypical lipomatous tumour (ALT)

What is an atypical lipomatous tumour? An atypical lipomatous tumour (ALT) is a type of cancer made up of fat. It is part of a group of cancers called sarcomas. Atypical lipomatous tumours can start anywhere in the body but the most common location for this tumour is the abdomen. Another name for this tumour …
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Well differentiated liposarcoma

What is a well-differentiated liposarcoma? Well-differentiated liposarcoma is a type of cancer made up of adipose tissue (fat). It is a slow-growing tumour that can start almost anywhere in the body.¬†Another name for this tumour is an atypical lipomatous tumour. What is the difference between a well-differentiated liposarcoma and an atypical lipomatous tumour? Well-differentiated liposarcoma …
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Dedifferentiated liposarcoma

What is dedifferentiated liposarcoma? Dedifferentiated liposarcoma is an aggressive type of cancer that typically starts in a deep location of the body such as the abdomen. It is called “dedifferentiated” because it arises from within a similar but less aggressive type of cancer called well-differentiated liposarcoma/atypical lipomatous tumour. The term “liposarcoma” means that the cancer …
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Intramuscular lipoma

What is an intramuscular lipoma? Intramuscular lipomas are non-cancerous tumours made up of fat. These tumours develop deep inside a muscle and they may feel like a lump. Often, intramuscular lipomas are not well separated from the surrounding normal muscle which can make it challenging for your surgeon to remove the tumour completely. What is …
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Lipoma

What is a lipoma? A lipoma is a non-cancerous tumour made up of fat cells. Most lipomas occur in the skin but this tumour can be found almost anywhere in the body. Can a lipoma turn into cancer over time? A lipoma cannot turn into cancer over time. However, tumours that are incompletely removed can …
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