MDM2

MDM2

What is MDM2? MDM2 is a gene that promotes cell division (the creation of new cells). Normal cells and those in non-cancerous tumours have two copies of the MDM2 gene. In contrast, cancerous tumours such as atypical lipomatous tumour/well differentiated liposarcoma have more than two copies of the MDM2 gene. How do pathologists test for …
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Atypical lipomatous tumour (ALT)

What is an atypical lipomatous tumour? An atypical lipomatous tumour (ALT) is a type of cancer made up of fat. ALTs can start anywhere in the body but the most common location for this tumour is the abdomen. Another name for an ALT is well differentiated liposarcoma. Is an atypical lipomatous tumour a type of …
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Well differentiated liposarcoma

What is a well-differentiated liposarcoma? Well-differentiated liposarcoma is a type of cancer made up of adipose tissue (fat). It is a slow-growing tumour that can start almost anywhere in the body.¬†Another name for this tumour is an atypical lipomatous tumour. What is the difference between a well-differentiated liposarcoma and an atypical lipomatous tumour? Well-differentiated liposarcoma …
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Dedifferentiated liposarcoma

What is dedifferentiated liposarcoma? Dedifferentiated liposarcoma is an aggressive type of cancer that typically starts in a deep location of the body such as the abdomen. It is called “dedifferentiated” because it arises from within a similar but less aggressive type of cancer called well-differentiated liposarcoma/atypical lipomatous tumour. The term ‘liposarcoma’ means that the cancer …
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Intramuscular lipoma

What is an intramuscular lipoma? Intramuscular lipomas are non-cancerous tumours made up of fat. These tumours develop deep inside a muscle and they may feel like a lump. Often, intramuscular lipomas are not well separated from the surrounding normal muscle which can make it challenging for your surgeon to remove the tumour completely. What is …
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Lipoma

What is a lipoma? A lipoma is a non-cancerous tumour made up of fat cells. Most lipomas occur in the skin but this tumour can be found almost anywhere in the body. Can a lipoma turn into cancer over time? A lipoma cannot turn into cancer over time. However, tumours that are incompletely removed can …
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