JAK2 (Janus kinase 2) is a gene that provides instructions for making a protein involved in how cells grow, divide, and respond to signals from the immune system. JAK2 is part of a family of related genes that also includes JAK1, JAK3, and TYK2. These genes all produce proteins that help cells communicate using a …
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In a molecular pathology report, the word rearrangement refers to a change in the DNA structure within a cell. DNA is usually organized into long strands called chromosomes, each containing many genes. A rearrangement happens when a piece of a chromosome breaks off and attaches somewhere else, either on the same chromosome or another chromosome. …
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What is in situ hybridization? In situ hybridization (ISH) is a laboratory test used to see genetic material, such as DNA or RNA, within cells or tissues. It is commonly used in medicine to identify and visualize specific genes or gene products and to detect infectious agents such as viruses. How does in situ hybridization …
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