PMS2 is a gene that produces a protein involved in DNA repair, specifically in a process called mismatch repair. This protein works closely with other mismatch repair proteins, including MLH1, MSH2, and MSH6, to detect and fix small errors that occur when DNA is copied in dividing cells. Together, these proteins play an important role …
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MLH1 is a gene that produces a protein involved in DNA repair, specifically in a process called mismatch repair. This protein works closely with other mismatch repair proteins, including PMS2, MSH2, and MSH6, to detect and fix small errors that occur when DNA is copied in dividing cells. Together, these proteins play an important role …
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What are mismatch repair proteins? Mismatch repair proteins (MMR) are a system inside all normal, healthy cells for fixing mistakes in our genetic material (DNA). The system is made up of different proteins and the four most common are called MSH2, MSH6, MLH1, and PMS2. The four MMR proteins MSH2, MSH6, MLH1, and PMS2 work …
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Endometrioid carcinoma is a type of ovarian cancer that starts from the epithelial cells, which are the cells that normally cover the surface of the ovary and line the glands inside the uterus. It accounts for about 10% of all ovarian cancers. Many cases of ovarian endometrioid carcinoma are associated with a condition called endometriosis. …
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