MTC

RET Mutations and Fusions in Thyroid Cancer

If your pathology report or genetic test results mention a RET mutation or a RET fusion, these refer to two distinct types of change in the RET gene that play important roles in different types of thyroid cancer. RET mutations — where a specific letter in the gene’s code is altered — are the primary …
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Medullary Thyroid Carcinoma: Understanding Your Pathology Report

Medullary thyroid carcinoma is a rare type of thyroid cancer that starts from C cells (also called parafollicular cells). The thyroid is a butterfly-shaped gland at the front of the neck. Most thyroid cancers begin in follicular cells, which make thyroid hormone. Medullary thyroid carcinoma differs because it arises from C cells, which produce a hormone …
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