pathology

Inflammatory myofibroblastic tumour (IMT)

What is an inflammatory myofibroblastic tumour? Inflammatory myofibroblastic tumour (IMT) is a rare type of tumour that typically behaves in a noncancerous manner. It can be found anywhere in the body including the abdomen, pelvis, urinary tract, digestive tract, female reproductive organs, head and neck, and lungs. Is inflammatory myofibroblastic tumour benign or malignant? Although …
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Pseudosarcomatous myofibroblastic proliferation

A pseudosarcomatous myofibroblastic proliferation is a non-cancerous growth that can develop after certain surgical procedures or manipulations. Although it may sometimes be mistaken for cancer under a microscope, this condition is entirely benign (non-cancerous). Other names for this condition include postoperative spindle cell nodule and pseudosarcomatous myofibroblastic neoplasm. Where are pseudosarcomatous myofibroblastic proliferations typically found? Pseudosarcomatous …
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Extranodal NK/T cell lymphoma

Extranodal NK/T cell lymphoma is a rare type of cancer that starts in natural killer (NK) cells or T cells, which are parts of the immune system. The term “extranodal” means that it typically begins outside the lymph nodes, often in areas like the nasal passages, skin, digestive system, or other organs. This type of …
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Bile duct adenoma

What is a bile duct adenoma? A bile duct adenoma is a noncancerous type of tumour found in the liver. It is made up of bile ducts, small channels that help move bile and other substances out of the liver. What causes a bile duct adenoma? We do not know what causes a bile duct …
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Perivascular epithelioid cell tumour (PEComa)

What is a perivascular epithelioid cell tumour? Perivascular epithelioid cell tumour (commonly referred to as a PEComa) is a relatively uncommon type of tumour made up of cells that are normally found on the outside of blood vessels. Another name for perivascular epithelioid cell tumour is angiomyolipoma (AML). Where in the body are perivascular epithelioid …
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Paget’s disease of the breast

Paget’s disease is a non-invasive type of breast cancer that involves the nipple and surrounding skin. It is considered non-invasive because the tumour cells are limited to a layer of the skin called the epidermis. Most tumours are believed to start in channels called ducts that run from the nipple to glands deep in the breast. …
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Polymorphous adenocarcinoma

Polymorphous adenocarcinoma (previously known as polymorphous low-grade adenocarcinoma) is a type of cancer that arises in the salivary glands. It typically occurs in the minor salivary glands found throughout the mouth and throat. This tumour is most commonly seen in the palate, but it can also occur in other areas such as the lip, buccal mucosa …
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Epithelial-myoepithelial carcinoma

Epithelial-myoepithelial carcinoma (EMC) is a type of salivary gland cancer. The tumour is described as a biphasic salivary gland neoplasm because it comprises two populations of cells: ductal (luminal) and myoepithelial (abluminal) cells. The most common location for epithelial-myoepithelial carcinoma is the parotid gland. However, the tumour can be found in any salivary glands, including …
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Urothelial papilloma

A urothelial papilloma is a benign (non-cancerous) tumour that develops from cells lining the inside surface of the urinary tract. While it usually forms in the bladder, it can appear anywhere along the urinary tract. After removal, some papillomas may regrow, but importantly, they do not become cancerous over time. Understanding the urinary tract The …
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Epithelioid sarcoma

Background: Epithelioid sarcoma is a type of soft tissue cancer. It is called epithelioid because the tumour cells look and behave like epithelial cells that are normally found on the outside or inside surface of any organ. Although epithelioid sarcoma can occur almost anywhere in the body, the most common location is the hand. What …
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