somatic mutation

BRCA1 and BRCA2 in Ovarian Cancer

If your pathology report or genetic test results mention BRCA1 or BRCA2, these refer to two genes that play a critical role in repairing damaged DNA. In ovarian cancer, BRCA testing is one of the most important molecular tests performed — not just because a mutation in either gene helps predict how the cancer will …
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What is a somatic mutation?

A somatic mutation is a change in a gene that occurs during a person’s lifetime in a specific group of cells. These mutations are not present at birth and are not passed down from parents. Instead, they develop in cells as they grow and divide. Somatic mutations are common in many types of cancer because …
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