special stain

What is periodic acid Schiff plus diastase (PAS-D)?

Periodic acid Schiff plus diastase or PAS-D is a special stain with various uses by pathologists. It is typically used in combination with the routine hematoxylin and eosin (H&E) stained slide. Common uses for PAS-D include: Intracellular mucin: PAS-D can help a pathologist differentiate between glycogen and mucin. When a PAS-D-stained slide is examined under …
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What is periodic acid Schiff (PAS)?

Periodic acid Schiff (also known as PAS) is a special stain test performed by pathologists to look for two types of chemicals in a tissue sample: a type of sugar called glycogen, and a type of protein called mucin. Pathologists often perform a PAS stain when they are trying to determine if the cells in …
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Grocott (GMS)

Grocott (also known as GMS) is a special stain test performed by pathologists to look for fungal microorganisms in a tissue sample. The most commonly identified fungal microorganisms are Candida and Pneumocystis. GMS may also be used to look for some types of bacteria, such as Actinomyces and Nocardia. When a GMS-stained slide is examined …
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What is a special stain?

A special stain is a specialized test pathologists use to examine tissue samples more closely. While the most common stain used by pathologists is called hematoxylin and eosin (H&E), sometimes additional details are needed that this standard stain cannot reveal. Special stains involve applying specific coloured dyes to tissue samples, highlighting particular cells, microorganisms, or …
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